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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 25.76
Human Site: T922 Identified Species: 47.22
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 T922 S M F A P L K T L P S Q Y L P
Chimpanzee Pan troglodytes XP_001138050 2188 240763 T936 S M F A P L K T L P S Q Y L P
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 T922 S M F A P L K T L P S Q Y L P
Dog Lupus familis XP_537704 2182 240593 S931 S M F A P L K S L P S Q C L P
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 T921 S M F A P L K T L P S H C L P
Rat Rattus norvegicus NP_001100505 2040 223488 P820 V G K L D L L P S G P S M P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 T919 S M F A P L K T L P S Q C L P
Chicken Gallus gallus XP_415884 2225 244861 T973 S M F A P L K T L P S Q C L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 G863 F K M E V E E G F C S P K P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 N1166 T R Y A P L T N L P S Q T Q P
Honey Bee Apis mellifera XP_393643 1982 216109 L762 S L M D Q T E L S V P Q R P L
Nematode Worm Caenorhab. elegans Q93442 2862 325119 R1085 T L E D D V E R I A V P G G V
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 93.3 93.3 N.A. 6.6 N.A. 53.3 13.3 0 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 6.6 N.A. 93.3 93.3 N.A. 13.3 N.A. 66.6 26.6 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 62 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 31 0 0 % C
% Asp: 0 0 0 16 16 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 8 0 8 24 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 54 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 8 0 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 54 0 0 0 0 0 8 0 0 % K
% Leu: 0 16 0 8 0 70 8 8 62 0 0 0 0 54 8 % L
% Met: 0 54 16 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 62 0 0 8 0 62 16 16 0 24 62 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 62 0 8 0 % Q
% Arg: 0 8 0 0 0 0 0 8 0 0 0 0 8 0 0 % R
% Ser: 62 0 0 0 0 0 0 8 16 0 70 8 0 0 8 % S
% Thr: 16 0 0 0 0 8 8 47 0 0 0 0 8 0 0 % T
% Val: 8 0 0 0 8 8 0 0 0 8 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 24 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _